Elderberry, or more technically, sambucus, is one of the most popular natural antivirals, and Aviva Romm, M.D., an integrative medicine doctor and a master herbalist, says it's her "go-to antiviral herb for early signs of the flu."
One study published in the Journal of Functional Food specifically looked at the influenza virus in vitro and found that elderberry extract"showed mild inhibitory effect at the early stages of the influenza virus cycle, with considerably stronger effect in the post-infection phase."
Supplementation with elderberry was also found to substantially reduce upper respiratory symptoms in a meta-analysis of research, which included 180 total participants, published in Complementary Theories in Medicine.
Romm recommends taking sambucas in tincture or syrup form—about 3 tablespoons a day for adults and 3 teaspoons per day for kids over 2 years old—at the earliest signs of symptoms.
That said, it may interact with some medications, according to a systematic review of elderberry and elderflower. So speak to your doctor before trying elderberry.
Curcumin, the main compound in turmeric, has been used in integrative medicine as far back as the 1700s.
In one study published in Antiviral Research, which specifically looked at Zika and chikungunya viruses in vitro, researchers found that the viruses "lost infectivity when incubated directly with curcumin or derivatives of curcumin, suggesting that curcumin alters the ability of the virus to infect cells." The researchers stated they believe curcumin reduces the viruses' ability to replicate, by keeping it from binding at the cell surface.
Curcumin has also demonstrated antiviral activity against several different types of viruses, according to a review of current research published in Frontiers in Microbiology.
Ellen Vora, M.D., who is board-certified in holistic and integrative medicine, says that you can take curcumin as a supplement (there's no one-size-fits-all dose, but a review of research published in Foodnoted that 500 to 2,000 milligrams has been used without any side effects) or cook with turmeric. She also recommends combining it with black pepper, which can increase its absorption rate.
Avoid taking curcumin if you're on any blood-thinning medications, like anticoagulants or antiplatelet drugs, according to researchers at Oregon State University. This can slow blood clotting and lead to bleeding and bruising.
3. Oregano Oil
Carvacrol is the primary active component in oregano oil, a potential natural antiviral that has been shown to break down viruses, reducing their ability to infect their host, according to the American Society for Microbiology.
Thymol, the other major component of oregano oil, may also possess antiviral qualities. In one in vitro study that was published in Planta Medica, thymol reduced the activity of the herpes virus by 90% within one hour.
Bindiya Gandhi, M.D., an American Board Family Medicine–certified physician, points out that oregano oil may also help fight inflammation—a hallmark of viral infections—and allergies. She recommends oregano oil capsules (taken as directed) over tinctures or drops since the oil can have a pungent flavor that can be off-putting. However, she says if you do take it in liquid form, put a few drops directly on your tongue every day.
If you're pregnant or have an iron deficiency, you should avoid taking oregano oil since it can negatively affect iron absorption.
Peppermint, or Mentha piperita, as it's officially known, is an herb that is said to have natural antiviral properties. In addition to menthol, which is found in the highest concentrations, it contains more than 40 compounds, like flavonoids, polyphenols, and tocopherols, that may play a role in keeping you healthy.
Peppermint oil, which is a concentrated form of the active compounds in peppermint, may be especially helpful. In one study that was published in Phytomedicine, researchers found that peppermint oil may reduce the viral activity of the herpes virus, when exposed to it in a controlled lab setting.
Romm recommends sticking to peppermint oil soft gels, which are widely available as a supplement and properly diluted, and avoiding self-medicating with essential oils at home. Also, you shouldn't apply peppermint oil directly to your skin, as it can cause burns and rashes. Romm also notes that pregnant women should also avoid peppermint oil.
Romm calls garlic, whose official name is Allium sativum L., "the original super-immunity herb." Garlic has been used as a therapeutic medicinal plant for centuries. Its main compound, called allicin, is said to have several health benefits, including antimicrobial activity.
Although there's been more research on garlic's effect on bacteria, a review published in the Avicenna Journal of Phytomedicine noted that studies have shown garlic extract may exhibit antiviral activityagainst several different types of viruses, like influenza and rhinovirus.
But the scant garlic you cook with likely isn't enough to fight off viral infections. You need concentrated doses, Moday says, "at the first sign of an infection, start eating one raw garlic clove daily, or use concentrated allicin extract."
Garlic may interact with blood-thinning medications and HIV medications, according to the National Center for Complementary and Integrative Health (NCCIH), a part of the National Institutes of Health (NIH). If you're currently on medication, check in with your doctor to make sure garlic is safe.
Next to elderberry, echinacea may be one of the most well-known natural antivirals. However, even though it's a popular choice for immunity, it's important to note that studies have found mixed results on whether it's effective.
In one in vitro study published in Virology Journal, echinacea extract interfered with viral entry into cells. The research noted that the extract may reduce the activity of several different types of viruses, too. However, other studies haven't shown any positive effects.
There are several different types of echinacea, but the most widely used, and most commonly studied, is Echinacea purpurea, which is available as a tincture, spray, tablet, or tea.
Since there has been limited human research, it's important to speak to your doctor before taking echinacea, especially if you have a pre-existing medical condition.
7. St. John's wort
Although the exact mechanisms of St. John's wort's natural antiviral activity aren't clear, researchers believe that the components in St. John's wort may alter proteins in the viruses, preventing them from fusing with cell membranes and causing infection, according to Herbal Medicine.
Vora typically recommends taking 450 milligrams of St. John's wort twice a day for a month and then increasing to 900 milligrams twice per day. However, since the supplement is potent, she advises working closely with a practitioner to make sure you're using it safely.
It's especially important to check in with your doctor before taking St. John's wort if you're on any type of medication. St. John's wort can interfere with anti-anxiety medication, antidepressants, pain medication, and birth control pills (to name a few), according to the NCCIH.
Ginger, formally known as Zingiber officinale Roscoe, has many active compounds, including phenols, terpenes, and organic acids. However, the health benefits of ginger are largely connected to its phenolic compounds, specifically gingerols and shogaols. Over the years, research has shown that ginger may prevent the growth of viruses (as well as bacteria and fungi), according to a research review in Foods.
In one in vitro study, researchers found fresh ginger stimulated mucosal cells to release IFN-β, a type of cytokine that contributes to counteracting a viral infection. Another clinical trial that involved 60 volunteers with confirmed hepatitis indicated that ginger extract may decrease the activity of hepatitis C viruses.
Romm recommends choosing fresh or powdered organic ginger and adding it to smoothies or other recipes or steeping it as a tea. You can also get more concentrated doses of ginger in supplement form.
While there's no definitive research, the NCCIH notes ginger may interact with blood-thinning medications, so talk to your doctor before taking ginger if you're on blood thinners.
Scrophularia is a family of herbal plants commonly called figworts. There are nearly 200 species of Scrophularia, but one particular species, called Scrophularia scorodonia, may be especially helpful in fighting off viruses.
According to one research review, when Scrophularia scorodonia was exposed in vitro to HCoV-22E9, a type of human coronavirus infection, it revealed it may help prevent the virus from attaching to, and penetrating into, the cells of the body.
Scrophularia scorodonia is sold as an herbal supplement called Xuán Shēn, but you can get other forms of Scrophularia species under the name "figwort." While there's no standard dosage used in studies, the manufacturer recommends 300 milligrams per day.
Scrophularia may interfere with certain medications, so talk to your doctor about any potential risks.
The research and history around natural antivirals is intriguing, but there is still no proven evidence that these treatments are effective. While you may choose to try natural antivirals and antiviral herbs, all the usual general health recommendations apply when it comes to preventing viral infections. Wash your hands, don't touch your face, eat plenty of vegetables and some fruits, exercise, and get some fresh air. It's also important to get enough good-quality sleep and manage your stress levels, which, as Moday points out, when lacking, are the No. 1 reason you get sick in the first place.
Again, if you are experiencing any symptoms of a viral infection, it's important to speak to your doctor before relying on any at-home remedy, including antiviral herbs.